Ceflen (Cefoperazone, Sulbactam) Injection

Generic brands for Cefoperazone, Sulbactam Injection  Available in India Brand Name Ceflen Generic Name Cefoperazone, Sulbactam Strength 1.5mg, 3gm Manufacturer Mylan Pharmaceuticals Pvt

Description

Description

This page contains brief details about the drug cefoperazone,sulbactam, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

Date of Approval

Cefoperazone + Sulbactam is an antibiotic medication developed by the U.S. Food And Drug Administration and initially approved in the year 1981, for treating serious infections such as urinary tract infections, respiratory tract infections, intra-abdominal infections, septicemia, meningitis, skin infections, bone infections, and endometritis.

Mechanism of Action of Cefoperazone, Sulbactam

Cefoperazone is an antibiotic that works by interfering with bacterial cell wall synthesis, leading to the destruction of the bacteria. Sulbactam, the beta-lactamase inhibitor, helps inactivate the beta-lactamase enzymes produced by certain bacteria. This prevents the breakdown of cefoperazone by these enzymes, enhancing its effectiveness against resistant bacteria.

Uses of Cefoperazone, Sulbactam

Cefoperazone + Sulbactam this combination is effective against a wide range of bacteria and this drug is commonly used to treat serious infections such as urinary tract infections, respiratory tract infections, intra-abdominal infections, septicemia, meningitis, skin infections, bone infections, and endometritis.

Cefoperazone, Sulbactam Dosage available

This injection is available with a dose of 2gm, 3gm and 1.5gm. Do not self-administer the Cefoperazone + Sulbactam injection. Your doctor will decide the duration and dose of your treatment based on the disease severity and other factors. It will be given as an intravenous infusion, and you will be monitored carefully for unwanted side effects.

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References

  1. Pfizer Limited, [Revised on April 2020] [ Accessed on 27th June 2021], https://labeling.pfizer.com/ShowLabeling.aspx?id=14800
  2. Pfizer, US Food and Drug Administration, [Revised on March 2015] [ Accessed on 27th June 2021],https://www.accessdata.fda.gov/drugsatfda_docs/label/2015/050551s043lbl.pdf
  3. Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Penicillins, cephalosporins, and other beta-lactam antibiotics, 12th edition, 2011, 1499.
  4. KD Tripathi, Essentials of Medical Pharmacology, Beta-lactam antibiotics, 7th edition, 2013, 728.