Cytlieva (Cytarabine) Injection

Generic brands for Cytarabine Injection  Available in India Brand Name Cytlieva Generic Name Cytarabine Strength 100mg, 500mg, 1000mg Manufacturer Allieva Pharma Pvt. Ltd.

Description

Description

This page contains brief details about the drug cytarabine, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

Date of Approval

Cytarabine is an antineoplastic agent that belongs to the class antimetabolite. Initially, FDA approved it on January 01, 1999, for its medical use.

Mechanism of Action of Cytarabine

Cytarabine is a cytotoxic drug that acts by primarily killing cells undergoing DNA synthesis. It works by slowing or stopping the growth of cancer cells in your body.

Uses of Cytarabine

Cytarabine is a prescription drug and it is used alone or with other chemotherapy medications to treat certain types of leukemias (a type of blood cancer with too many white blood cells), including acute myeloid leukemia (AML) and chronic myelogenous leukemia (CML). It is also indicated to use alone or with other chemotherapy drugs to treat and prevent meningeal leukemia (cancer in the membrane that covers and protects the spinal cord and brain).

Cytarabine Dosage available

A trained healthcare professional will give you Cytarabine in a hospital setting. It is available as an injection for solution. This medicine may be given by solution for injection/infusion (using a syringe) under the skin (subcutaneous) or into a vein (intravenously) or into a muscle (intramuscularly), or into the spine (intrathecal). Your doctor will decide the dose, route of administration, and duration of the treatment based on your disease condition, severity, and other factors.

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News/Updates

References

  1. Cytarabine Injection. [cited 2020 Dec 3]. Available from: https://www.accessdata.fda.gov/drugsatfda_docs/label/2020/071868s032lbl.pdf
  2. Cytarabine Injection Solution 100 mg/ml – Summary of Product Characteristics (SmPC) – (emc) [Internet]. www.medicines.org.uk. [revised on 2020] [cited 2023 Mar 30]. Available from: https://www.medicines.org.uk/emc/product/1570/smpc
  3. Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Cytotoxic agents, 12th edition, 2011, 1698 – 1699.
  4. KD Tripathi, Essentials of Medical Pharmacology, Anticancer drugs, 7th edition, 2013, 864 – 865.