Dapaglyn M (Dapagliflozin+Metformin) Tablet

Generic brands for Dapagliflozin+Metformin Tablet Available in India Brand Name Dapaglyn M Generic Name Dapagliflozin+Metformin Strength 5mg/1000mg, 10mg/1000mg, 10mg/500mg, 500mg, 1000mg Manufacturer Zydus Cadila  

Description

Description

This page contains brief details about the drug dapagliflozin,metformin, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

Date of Approval

Dapagliflozin + Metformin is an anti-diabetic drug. Dapagliflozin belongs to the group of medications called sodium-glucose co-transporter. Metformin belongs to the class of medications called biguanides. FDA approved this medicine on October 30, 2014, for its medical use.

Mechanism of Action of Dapagliflozin+Metformin

Dapagliflozin reduces glucose reabsorption and lowers the renal threshold for glucose. It works by removing excess sugar from your body via your urine and lowering the sugar in your blood. Metformin primarily decreases hepatic glucose production and decreases intestinal absorption of glucose. It works mainly by inhibiting glucose production in the liver.

Uses of Dapagliflozin+Metformin

Dapagliflozin + Metformin is available as a tablet.  It treats type 2 diabetes mellitus in patients aged 18 years and older. This combination of medicines is taken by mouth (orally).

Dapagliflozin+Metformin Dosage available

It is an orally available prescription drug. Your doctor will decide the dose and duration of dapagliflozin + metformin based on the blood sugar and other factors. Always take this medicine as prescribed by your doctor. Take the tablet at the same time with food. Do not break, chew, crush, or break the tablet. Swallow the whole tablet with water.

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References

  1. Xigduo 5 mg/850 mg film coated tablets – Patient Information Leaflet (PIL) – (emc). www.medicines.org.uk. [Revised 30 Nov]  [cited 2023 Jun 5]. Available from: https://www.medicines.org.uk/emc/product/5293/pil
  2. AstraZeneca Pharmaceuticals – Xigduo 5 mg/850 mg film coated tablets. Access.fda.gov. [Revised 2017 Jul] [cited 2023 Jun 5]. Available from: https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/205649s008lbl.pdf
  3. KD Tripathi, Essentials of Medical Pharmacology, Insulin, oral hypoglycaemic drugs and glucagon, 7th edition, 2013, 278.
  4. Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Endocrine pancreas and pharmacotherapy of diabetes mellitus and hypoglycaemia, 12th edition, 2011, 1258-1259.