Emtux (Rituximab) Injection

Generic brands for Rituximab Injection Available in India Brand Name Emtux Generic Name Rituximab Strength 100mg, 500mg Manufacturer Emcure Pharmaceuticals Ltd

Description

Description

This page contains brief details about the drug rituximab, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

Date of Approval

Rituximab is an immunomodulatory monoclonal antibody (a protein that attaches to a specific target) that was approved for its medical use on 26th November 1997.

Mechanism of Action of Rituximab

Rituximab Injection is a biological agent that belongs to the category of medications called monoclonal antibodies. It specifically targets and binds to the CD20 receptors, resulting in a significant decrease in the inflammatory mediators. The medicine inhibits the availability of B cells by depleting them and eventually stops the growth and multiplication of cancer cells.

Uses of Rituximab

Rituximab Injection has been developed to treat non-Hodgkin’s lymphoma, mature B-cell acute leukemia, chronic lymphocytic leukemia, granulomatosis, rheumatoid arthritis, and pemphigus vulgaris in patients who have not responded adequately to other treatments.

Rituximab Dosage available

Rituximab is available as a single-use vial of injection intended for administration as an intravenous infusion. It is available in doses of 100mg and 500mg. The usual recommended starting dose is 375mg/m2. Your doctor will decide the dose, dosage, and duration of the treatment based on your medical condition.

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News/Updates

References

  1. Genentech Inc., U.S. Food and Drug Administration, [Revised on Dec 2021] [Accessed on 15th Oct 2022], https://www.gene.com/download/pdf/rituxan_prescribing.pdf
  2. Ahmed A. Negm & Daniel E. Furst, Nonsteroidal Anti-Inflammatory Drugs, Disease-Modifying Antirheumatic Drugs, Nonopioid Analgesics, & Drugs Used in Gout, Lange’s Basic & Clinical Pharmacology, 14th Edition, 2018, 642-666.