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Endoxan (Cyclophosphamide) Tablet
Generic brands for Cyclophosphamide Tablet Available in India Brand Name Endoxan Generic Name Cyclophosphamide Strength 1gm/ 50mg, 50mg, 200mg, 500gm Manufacturer Zydus Cadila
Description
Description
This page contains brief details about the drug cyclophosphamide, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Date of Approval
Cyclophosphamide is a chemotherapy medication developed by the U.S. Food And Drug Administration for treating various malignancies (abnormal production of cells is called cancer and if they spread to other organs then they are called malignancies).
Mechanism of Action of Cyclophosphamide
Cyclophosphamide slows or stops the growth of cancer cells by damaging the hereditary material (DNA and RNA) of the cancer cells. In nephrotic syndrome, it works by suppressing the body’s immune system.
Uses of Cyclophosphamide
Cyclophosphamide helps to treat various malignancies (abnormal production of cells is called cancer and if they spread to other organs then they are called malignancies). Cyclophosphamide can be used to treat malignant lymphomas (cancers that start from the lymphatic system of the body- vessels, fluid, and lymphoid tissue) such as Hodgkin’s disease, lymphocytic lymphoma, and mixed-cell type lymphoma.
Cyclophosphamide Dosage available
Cyclophosphamide is available in the form of a tablet and injections. The recommended Cyclophosphamide dose for tablets is 50mg and injection is 1gm, 200mg, 500mg, 1000mg . Depending on your age, weight, and disease condition, your doctor will determine your appropriate dose and duration. Do not stop using this medicine unless your doctor instructs you.
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News/Updates
References
- Baxter, Electronic medicines compendium (emc), [ Revised on June 2016] [ Accessed on 8th April 2021], https://www.medicines.org.uk/emc/product/1815/smpc
- Baxter, US Food and Drug Administration, [ Revised on May 2013] [ Accessed on 7th April 2021], https://www.accessdata.fda.gov/drugsatfda_docs/label/2013/012141s090,012142s112lbl.pdf
- KD Tripathi, Essentials of Medical Pharmacology, Anticancer drugs, 7th edition, 2013, 860.