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Herhope (Trastuzumab) Injection
Generic brands for Trastuzumab Injection Available in India Brand Name Herhope Generic Name Trastuzumab Strength 150mg, 440mg Manufacturer Torrent Pharmaceuticals Ltd
Description
Description
This page contains brief details about the drug trastuzumab, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Date of Approval
Trastuzumab is a monoclonal antibody that was approved for its medical use on 25th September 1998.
Mechanism of Action of Trastuzumab
Trastuzumab Injection is a biological agent that acts as targeted drug therapy in cancer treatment. It is classified as a monoclonal antibody belonging to the class a HER2/neu receptor antagonists. HER2 or human epidermal growth factor receptor 2 is a protein present in high concentrations on the surface of cancer cells of the breast and gastric region. Trastuzumab Injection works by binding with these receptors, ultimately inhibiting the growth of cancer cells.
Uses of Trastuzumab
Trastuzumab Injection has been developed to treat solid tumors by injecting it as an intravenous infusion. Trastuzumab Injection has been approved to treat HER2 overexpressing breast cancer and stomach cancer (gastro-oesophageal Junction adenocarcinoma).
Trastuzumab Dosage available
Trastuzumab is available as multi dose vial injections in the doses 150 mg and 440 mg. It is intended for intravenous infusion only and not for IV push or bolus.
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News/Updates
References
1. Genentech, Inc., US Food & Drug Administration, [Revised on Feb 2021] [Accessed on 29th Aug 2022], https://www.gene.com/download/pdf/herceptin_prescribing.pdf
2. Anton Wellstein, Giuseppe Giaccone, Michael B. Atkins, and Edward A. Sausville, Pathway-Targeted Therapies: Monoclonal Antibodies, Protein Kinase Inhibitors, and Various Small Molecules, Goodman & Gilman’s Pharmacological Basis of Therapeutics, 13th Edition, 2018, 1203-1236.