Instgra (Dolutegravir) Tablet

Generic brands for Sofosbuvir + Velpatasvir Tablet Available in India Brand Name Velpas S Generic Name Sofosbuvir + Velpatasvir Strength Manufacturer Samarth Life Sciences Pvt. Ltd  

Description

Description

This page contains brief details about the drug dolutegravir, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

Date of Approval

Dolutegravir was approved as antiretroviral medication by FDA on 12/08/2013 to treat HIV infection.

Mechanism of Action of Dolutegravir

Dolutegravir Tablet is an antiretroviral medication belonging to the category of HIV integrase inhibitors. It works by increasing the number of CD4 T cells and stimulates the immune system to fight against infections. It helps reduce the viral load of HIV in the blood and lowers the severity of HIV infection.

Uses of Dolutegravir

Dolutegravir has been developed to treat Human Immunodeficiency Virus (HIV-1) in adults and children infected with HIV 1.

Dolutegravir Dosage available

Dolutegravir is available as film coated tablets and oral suspension. The tablets are available in the dose 50mg. The usual recommended dosage of Dolutegravir is one tablet everyday with or without food.

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News/Updates

References

  1. KD Tripathi, Antiviral Drugs (Anti-retrovirus), Essentials of Medical Pharmacology, 8th Edition, 2019, 860-872.
  2. GlaxoSmithKline, U.S. Food and Drug Administration, [Revised on Oct 2022] [Accessed on 13th Oct 2022], https://gskpro.com/content/dam/global/hcpportal/en_US/Prescribing_Information/Tivicay/pdf/TIVICAY-PI-PIL-IFU.PDF#page=1
  3. Kandel CE, Walmsley SL, Dolutegravir – a review of the pharmacology, efficacy, and safety in the treatment of HIV, Drug Des Devel Ther., 2015, 7(9), 3547-55, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4500604/pdf/dddt-9-3547.pdf