Kryxana (Ribociclib) Tablet

Description

Description

This page contains brief details about the drug ribociclib, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

Date of Approval

Ribociclib is an anticancer medication containing the active ingredient ribociclib. Cancer is a condition in which cells multiply uncontrolled and abnormally. It is used in women to treat a type of breast cancer (hormone receptor-positive, HER2-negative breast cancer) that is locally advanced or has spread to other parts of the body.  This medication is given in combination with other medications. It can also be used to treat endometrial cancer in combination with other drugs. It works by inhibiting the activity of certain proteins, which regulate cell growth and division. By blocking these proteins, it can slow down or stop the growth of cancer cells. It is not recommended for adolescents and children under 18 years of age.

Ribociclib was developed by Novartis Pharmaceuticals and was approved by the U.S. Food and Drug Administration (FDA) on 13 March 2017. It was initially approved for use in combination with an aromatase inhibitor as initial endocrine-based therapy for postmenopausal women with hormone receptor-positive, HER2-negative advanced, or metastatic breast cancer. Before taking this medication, it is vital to inform your doctor if you have any signs of infections (fever, mouth ulcers, or sore throat), liver disorders, heart disorders, or if you are allergic to peanut or soya.  You should not drink grapefruit juice or eat grapefruits during the treatment with this tablet.  It should not be used in persons with a known hypersensitivity or allergy to Kryxana 200 mg Tablet or any of its components.

Mechanism of Action of Ribociclib

Ribociclib works by inhibiting the activity of two proteins called CDK4 and CDK6, which regulate cell growth and division. By blocking these proteins, Ribociclib can slow down or stop the growth of cancer cells.

Uses of Ribociclib

Ribociclib is a medication used to treat certain types of breast cancer.  Ribociclib is used in combination with other anticancer medications  to treat advanced or metastatic (cancer that can spread to other regions of the body) breast cancer. It can also be used in combination with fulvestrant for women who have gone through menopause and have metastatic breast cancer.

Ribociclib Dosage available

Ribociclib is usually taken orally, with or without food. The tablets should be swallowed whole with a glass of water and not crushed, chewed or broken. The dosage and frequency of Ribociclib will depend on a variety of factors, including the patient’s age, weight, overall health, and the type and stage of cancer being treated. It’s important to follow the dosing instructions provided by a healthcare provider, and not to adjust the dosage or frequency without consulting with them first.