Lupinem (Cilastatin+Imipenem) Injection

Description

Description

This page contains brief details about the drug cilastatin,imipenem, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

Date of Approval

The U.S. FDA approved cilastatin + imipenem in 1985. It is used in treating various complex infections in the abdominal region, lung-related infections like pneumonia, and those occurring around the time of childbirth. Additionally, it proves effective against complicated urinary tract infections as well as skin and soft tissue infections. Moreover, this medicine finds utility in managing patients with low white blood cell counts and suspected bacterial-induced fevers. Furthermore, it serves as a viable option for treating bloodstream infections potentially linked to the types of infections.

Mechanism of Action of Cilastatin+Imipenem

Cilastatin acts as a blocker of renal dehydropeptidase-I. Because Imipenem, the antibiotic, is broken down by this enzyme found in the kidney, cilastatin is given alongside imipenem to prevent its breakdown and keep it effective.

Uses of Cilastatin+Imipenem

Cilastatin + imipenem is used to induce muscle relaxation in tracheal tube insertion for artificial ventilation and in intensive care unit surgery (ICU).

Cilastatin+Imipenem Dosage available

This medicine is given only in a hospital setup by a healthcare provider. cilastatin + imipenem will be given to you by your doctor. It is given intravenously (into a vein), either as single injections or as a continuous infusion (a drip). Your physician will decide the dosage and frequency of this injection based on the severity of your disease and other factors.