Mamofen (Tamoxifen Citrate) Tablet

Generic brands for Tamoxifen Citrate Tablet Available in India Brand Name Mamofen Generic Name Tamoxifen Citrate Strength 10mg, 20mg Manufacturer Khandelwal Laboratories Pvt. Ltd

Description

Description

This page contains brief details about the drug tamoxifen citrate, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

Date of Approval

Tamoxifen citrate is an anti-estrogen medication developed by the U.S. Food And Drug Administration and initially approved on 29 Oct 1998, for treating breast cancer and infertility.

Mechanism of Action of Tamoxifen Citrate

Tamoxifen citrate Tablet competes with estrogen (sex hormone) for binding to the estrogen receptor, decreases the estrogen receptor-dependent growth in breast tissue, and slows down the growth of cancer cells.

Uses of Tamoxifen Citrate

Tamoxifen citrate helps to treat and prevent breast cancer. It is also used to treat infertility in women caused by a failure to produce and release eggs properly. Cancer is a disorder in which cells multiply in an uncontrolled and abnormal manner.

Tamoxifen Citrate Dosage available

Tamoxifen citrate is a prescription medicine available as a tablet in two doses, Tamoxifen citrate 10mg and 20mg. Do not crush, chew, or open the medicine. Your physician will decide the correct dosage and duration based on age, body weight, and disease condition. Only stop taking the tablet if your doctor advises you to stop.

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References

  1. Wockhardt UK Limited, Electronic medicines compendium (emc), [ Revised on July 2018] [ Accessed on 16th June 2023], https://www.medicines.org.uk/emc/files/pil.2248.pdf
  2. AstraZeneca Pharmaceuticals LP, US Food and Drug Administration, [ Revised on Aug 2004] [Accessed on 16th June 2023], https://www.accessdata.fda.gov/drugsatfda_docs/label/2005/17970s053lbl.pdf
  3. Goodman & Gilman’s, The Pharmacological Basis of Therapeutics, Estrogens and progestins, 12th edition, 2011, 1177 – 1178.
  4. KD Tripathi, Essentials of Medical Pharmacology, Estrogens, progestins and contraceptives, 7th edition, 2013, 313.