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Midgram (Midodrine) Tablet
Generic brands for Midodrine Tablet Available in India Brand Name Midgram Generic Name Midodrine Strength 2.5mg Manufacturer Ingram Biosciences Pvt Ltd
Description
Description
This page contains brief details about the drug midodrine, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Date of Approval
Midodrine is an antihypotensive drug approved for its medical use in 1996
Mechanism of Action of Midodrine
The active metabolite of Midodrine is an alpha1-agonist that works by activating the alpha-adrenergic receptors to exert its effects. It constricts blood vessels and increases blood pressure.
Uses of Midodrine
It helps to treat orthostatic hypotension ( low blood pressure after sitting or lying down).
Midodrine Dosage available
The recommended starting dose of Midodrine tablet is 2.5 mg thrice daily with or without food. This dose can be increased weekly to 10 mg three times daily, which is the standard maintenance dose of 30 mg daily. Do not take this medication after the evening or less than three to four hours before bedtime.
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References
- Goodman & Gilman’s, The Pharmacological Basics of Therapeutics, Adrenergic agonists and antagonists, 12th edition, 2011,294-295.
- Brancaster Pharma Limited, Electronic medicines compendium (EMC), [ Revised on January 2021], [Accessed on 7th September 2022], https://www.medicines.org.uk/emc/files/pil.2265.pdf
- Shrine US Inc., US Food and Drug Administration, [ Revised on January 2017] [Accessed on 7th September 2022], https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/019815s010lbl.pdf