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Mistaurin (Midostaurin) Capsule
Generic brands for Midostaurin Capsule Available in India Brand Name Mistaurin Generic Name Midostaurin Strength 25mg Manufacturer Glenmark Pharmaceuticals
Description
Description
This page contains brief details about the drug midostaurin, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Date of Approval
Midostaurin is an anticancer medication which was approved for its medical use on April 2017.
Mechanism of Action of Midostaurin
Midostaurin is an anticancer medication belonging to the category of medications called kinase inhibitors. It acts against the receptors and proteins that facilitate the mutation of FLT3 gene, interrupts cancer cell signaling, and eventually stops the growth and spread of cancer cells.
Uses of Midostaurin
Midostaurin is a prescription medicine developed to treat acute myeloid leukemia caused by a mutation in FLT3 genes. It is also indicated to treat aggressive system mast cytosis, systemic mast cytosis with hematological neoplasm, and mast cell leukemia.
Midostaurin Dosage available
Midostaurin is available in form of Capsules in the dose 25mg. The usual recommended dosing is 50mg twice daily with food for acute myeloid leukemia and 100mg twice daily for aggressive systemic mast cytosis and systemic mast cytosis. Swallow Midostaurin Capsule whole with a glass of water.
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News/Updates
References
- Novartis, US Food & Drug Administration, [Revised on Nov 2021] [Accessed on 25th Oct 2022], https://www.novartis.com/us-en/sites/novartis_us/files/rydapt.pdf
- Anton Wellstein, Giuseppe Giaccone, Michael B. Atkins, and Edward A. Sausville, Pathway-Targeted Therapies: Monoclonal Antibodies, Protein Kinase Inhibitors, and Various Small Molecules, Goodman & Gilman’s Pharmacological Basis of Therapeutics, 13th Edition, 2018, 1203-1236.