Neomustin (Bendamustine) Injection

Description

Description

This page contains brief details about the drug bendamustine, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

Date of Approval

Bendamustine is an antineoplastic drug that belongs to the category of medicines known as alkylating agents. It was approved by the FDA in 2008 to treat certain types of cancers.

Mechanism of Action of Bendamustine

It is an alkylating drug, which works by causing DNA damage and disrupting the cell cycle, leading to cancer cell death. It forms covalent bonds with DNA, inhibits DNA repair enzymes, and blocks cell cycle progression. Bendamustine is used as a cytotoxic drug that kills cancer cells by inhibiting their DNA and cell cycle.

Uses of Bendamustine

Bendamustine is an alkylating agent used in the treatment of Chronic lymphocytic leukaemia (cancer of blood and bone marrow), Non-Hodgkin’s lymphomas (cancer that forms in the lymph system, part of the immune system), and Multiple myeloma(cancer of plasma cells, type of white blood cell).

Bendamustine Dosage available

Bendamustine is a prescription drug available in injection form. This injection will be given intravenously into a vein in your arm or hand by a healthcare professional in a hospital setting. Do not self-administer this medicine. Treatment should not be started if your white blood cells (leukocytes) have fallen to counts below determined levels. Your doctor will determine these values at regular intervals. The dose of the injection will be decided by your doctor based on your disease condition and other factors. Bendamustine Injection is usually given about 30 minutes before you receive your anti-cancer medicine (chemotherapy) or right before anaesthesia for surgery. During the infusion, you will be monitored for any side effects or reactions to the medication. The infusion usually takes several hours to complete, and you may need to receive multiple infusions over the course of several weeks.