Pobix (Polymyxin B) Injection

Description

Description

This page contains brief details about the drug polymyxin b, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

Date of Approval

Polymyxin B is an antibiotic used in gram-negative infection treatment.

Mechanism of Action of Polymyxin B

Polymyxin B acts by disrupting the outer membrane of Gram-negative bacteria. It binds to and interacts with the lipopolysaccharide layer, a crucial bacterial cell wall component, causing membrane destabilization. This leads to increased permeability, leakage of cell contents, and eventual cell death. By targeting the outer membrane, this medication effectively neutralizes Gram-negative bacteria, making it particularly valuable in treating infections caused by these bacteria, especially in cases of multidrug resistance where other antibiotics may not be effective.

Uses of Polymyxin B

Polymyxin B treats severe bacterial infections, especially those caused by Gram-negative bacteria and multi-drug resistant strains. It is commonly used for infections like urinary tract infections, pneumonia, and ventilator-associated pneumonia caused by multidrug-resistant bacteria. This medication is available in intravenous and topical formulations, making it effective for systemic and localized bacterial infections.

Polymyxin B Dosage available

Polymyxin B should be taken exactly as prescribed by a healthcare professional. It is available in various forms, such as tablets or capsules. The dosage and frequency depend on the medical condition being treated. This medication can be taken with or without food, and patients should not adjust the dosage or stop taking it without medical guidance. Following the doctor’s instructions is very important, and if you experience any possible side effects, inform your healthcare provider immediately.