Revolade (Eltrombopag) Tablet

Generic brands for Eltrombopag Tablet Available in India Brand Name Revolade Generic Name Eltrombopag Strength 25mg, 50mg Manufacturer Novartis India Ltd

Description

Description

This page contains brief details about the drug eltrombopag, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

Date of Approval

Eltrombopag was first approved by the U.S. FDA on November 20, 2008, for treatment of  thrombocytopenia, chronic hepatitis C, and patients with severe aplastic anemia.

Mechanism of Action of Eltrombopag

Eltrombopag works by stimulating megakaryocytes (the large bone marrow cells) that are responsible for producing platelets. By raising the number of platelets in the blood, Eltrompag prevents bleeding and bruising.

Uses of Eltrombopag

Eltrombopag has been developed to treat immune (primary thrombocytopenia (ITP) or hepatitis C virus (HCV) infection and also treats low blood counts caused by severe aplastic anemia.

Eltrombopag Dosage available

Eltrombopag is available as a tablet to be taken with an empty stomach (1 hour before or 2 hours after a meal). The usual starting dose of an Eltrombopag tablet is 50 mg once daily. Avoid crushing, opening, or dissolving the tablet; swallow it whole with a glass of water. Take this medication as prescribed by your physician. Avoid dairy foods (such as cheese or butter), milk or milkshakes, antacids, and supplements containing iron, aluminum, magnesium, calcium, selenium, zinc, or calcium for 2 hours after or 4 hours before taking this medication.

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References

  1. GlaxoSmithKline, US Food and Drug Administration, [ Revised on October 2008] [ Accessed on 12th September 2022], https://www.accessdata.fda.gov/drugsatfda_docs/label/2008/022291lbl.pdf
  2. Novartis Pharmaceuticals UK Limited, Electronic medicines compendium (EMC), [ Revised on Jan 2022] [ Accessed on 12th September 2022], https://www.medicines.org.uk/emc/files/pil.508.pdf
  3. Douglas B.cines et al; Safety and efficacy of romiplostim in splenectomized and nonsplenectomized patients with primary immune thrombocytopenia; Haematologica; Published on August 2017; Accessed on 12/09/2022; https://www.haematologica.org/article/view/8154