Vincreta (Vincristine Sulphate) Injection

Description

Description

This page contains brief details about the drug vincristine sulphate, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

Date of Approval

Vincristine sulphate is a chemotherapy medication containing the active constituent vincristine sulphate. It belongs to a class of drugs called vinca alkaloids, which inhibit the growth of cancer cells. This medication treats blood, head, breast, neck, kidney, bone, or lung cancers. It treats rhabdomyosarcoma (cancer that affects muscle tissue) and neuroblastoma (cancer that develops from immature nerve cells). It may also treat multiple myeloma (cancer of plasma cells), thyroid cancer, and a blood disorder known as idiopathic thrombocytopenic purpura (ITP). Cancer is a disorder in which cells multiply uncontrolled and abnormally.

Vincristine sulphate was first approved by the FDA in 1963 for treating acute lymphocytic leukemia (ALL). Since then, it has received additional approvals for treating other types of cancer. Like all chemotherapy drugs, it can cause side effects, such as nausea, vomiting, constipation, hair loss, and fatigue. Patients should discuss the potential benefits and risks of treatment with their doctor.

Mechanism of Action of Vincristine Sulphate

The therapeutic effect of vincristine sulphate inhibits the growth and spread of cancer cells. Vincristine sulphate disrupts the formation and function of microtubules, which are structures inside cells that help with cell division and movement. By interfering with microtubule function, this medication can prevent cancer cells from dividing and multiplying and can also cause them to die.

Uses of Vincristine Sulphate

Vincristine sulphate is used to treat various types of cancer, including blood cancers such as acute lymphocytic leukemia (ALL), head and neck cancers, breast cancer, kidney cancer, bone cancer, and lung cancer. It is also used to treat idiopathic thrombocytopenic purpura (a condition in which the immune system attacks and destroys platelets cells) and multiple myeloma (a type of blood cancer that affects plasma cells). In addition, this medication is used to treat rhabdomyosarcoma (cancer that forms in the body’s soft tissues) and neuroblastoma (cancer that develops in certain nerve cells). It may also be used to treat thyroid cancer.

Vincristine Sulphate Dosage available

A healthcare professional usually administers vincristine sulphate intravenous injection (IV) in a hospital or clinical setting. It should not be taken orally or applied topically to the skin. If you miss a dose, do not double the dose to make up for the missed one.