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Category: Breast Cancer
Gemcitabine
Description
This page contains brief details about the drug gemcitabine, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Date of Approval
The U.S. FDA approved Gemcitabine as a chemotherapeutic anticancer medication to treat bladder, breast, ovarian, pancreatic, and non-small cell lung cancers on 10th January 1995.
Mechanism of Action of Gemcitabine
Gemcitabine is a cytotoxic agent belonging to the category of medications called antimetabolites. It inhibits DNA polymerase enzyme, breaks the DNA strands, interferes with cell signalling and eventually prevents the multiplication of cancer cells. Gemcitabine is prescribed alone and also in combination with other anticancer medications like Cisplatin and Carboplatin.
Uses of Gemcitabine
Gemcitabine has been developed to treat ovarian cancer, breast cancer, non-small cell lung cancer, and pancreatic cancer in patients who have failed to respond to previous therapies.
Gemcitabine Dosage available
Gemcitabine is available for administration as an intravenous infusion that is injected through the veins of patients with ovarian, breast, and non-small cell lung cancer. Your physician will choose the dosage and administration frequency based on your medical condition and type of cancer because it differs for each person.
Tamoxifen Citrate
Description
This page contains brief details about the drug tamoxifen citrate, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Date of Approval
Tamoxifen citrate is an anti-estrogen medication developed by the U.S. Food And Drug Administration and initially approved on 29 Oct 1998, for treating breast cancer and infertility.
Mechanism of Action of Tamoxifen Citrate
Tamoxifen citrate Tablet competes with estrogen (sex hormone) for binding to the estrogen receptor, decreases the estrogen receptor-dependent growth in breast tissue, and slows down the growth of cancer cells.
Uses of Tamoxifen Citrate
Tamoxifen citrate helps to treat and prevent breast cancer. It is also used to treat infertility in women caused by a failure to produce and release eggs properly. Cancer is a disorder in which cells multiply in an uncontrolled and abnormal manner.
Tamoxifen Citrate Dosage available
Tamoxifen citrate is a prescription medicine available as a tablet in two doses, Tamoxifen citrate 10mg and 20mg. Do not crush, chew, or open the medicine. Your physician will decide the correct dosage and duration based on age, body weight, and disease condition. Only stop taking the tablet if your doctor advises you to stop.
Docetaxel
Description
This page contains brief details about the drug docetaxel, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Date of Approval
Docetaxel is a chemotherapy medication that was approved to be used for its medical use on 19th May 2004.
Mechanism of Action of Docetaxel
Docetaxel works by inhibiting the microtubule structures found in the cells. These microtubules help the cancer cells in proliferating. Hence, inhibition of these structures aids in slowing down the growth of the cancer cells.
Uses of Docetaxel
Docetaxel is indicated for treating different types of cancers, which include the following, non-small cell lung cancer, breast cancer, prostate cancer, stomach cancer and head and neck cancer.
Docetaxel Dosage available
Docetaxel concentrate for solution for infusion (injections) is available in three doses of 20mg, 80mg and 120mg.
Vincristine Sulphate
Description
This page contains brief details about the drug vincristine sulphate, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Date of Approval
Vincristine sulphate is a chemotherapy medication containing the active constituent vincristine sulphate. It belongs to a class of drugs called vinca alkaloids, which inhibit the growth of cancer cells. This medication treats blood, head, breast, neck, kidney, bone, or lung cancers. It treats rhabdomyosarcoma (cancer that affects muscle tissue) and neuroblastoma (cancer that develops from immature nerve cells). It may also treat multiple myeloma (cancer of plasma cells), thyroid cancer, and a blood disorder known as idiopathic thrombocytopenic purpura (ITP). Cancer is a disorder in which cells multiply uncontrolled and abnormally.
Vincristine sulphate was first approved by the FDA in 1963 for treating acute lymphocytic leukemia (ALL). Since then, it has received additional approvals for treating other types of cancer. Like all chemotherapy drugs, it can cause side effects, such as nausea, vomiting, constipation, hair loss, and fatigue. Patients should discuss the potential benefits and risks of treatment with their doctor.
Mechanism of Action of Vincristine Sulphate
The therapeutic effect of vincristine sulphate inhibits the growth and spread of cancer cells. Vincristine sulphate disrupts the formation and function of microtubules, which are structures inside cells that help with cell division and movement. By interfering with microtubule function, this medication can prevent cancer cells from dividing and multiplying and can also cause them to die.
Uses of Vincristine Sulphate
Vincristine sulphate is used to treat various types of cancer, including blood cancers such as acute lymphocytic leukemia (ALL), head and neck cancers, breast cancer, kidney cancer, bone cancer, and lung cancer. It is also used to treat idiopathic thrombocytopenic purpura (a condition in which the immune system attacks and destroys platelets cells) and multiple myeloma (a type of blood cancer that affects plasma cells). In addition, this medication is used to treat rhabdomyosarcoma (cancer that forms in the body’s soft tissues) and neuroblastoma (cancer that develops in certain nerve cells). It may also be used to treat thyroid cancer.
Vincristine Sulphate Dosage available
A healthcare professional usually administers vincristine sulphate intravenous injection (IV) in a hospital or clinical setting. It should not be taken orally or applied topically to the skin. If you miss a dose, do not double the dose to make up for the missed one.
Trastuzumab
Description
This page contains brief details about the drug trastuzumab, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Date of Approval
Trastuzumab is a monoclonal antibody that was approved for its medical use on 25th September 1998.
Mechanism of Action of Trastuzumab
Trastuzumab Injection is a biological agent that acts as targeted drug therapy in cancer treatment. It is classified as a monoclonal antibody belonging to the class a HER2/neu receptor antagonists. HER2 or human epidermal growth factor receptor 2 is a protein present in high concentrations on the surface of cancer cells of the breast and gastric region. Trastuzumab Injection works by binding with these receptors, ultimately inhibiting the growth of cancer cells.
Uses of Trastuzumab
Trastuzumab Injection has been developed to treat solid tumors by injecting it as an intravenous infusion. Trastuzumab Injection has been approved to treat HER2 overexpressing breast cancer and stomach cancer (gastro-oesophageal Junction adenocarcinoma).
Trastuzumab Dosage available
Trastuzumab is available as multi dose vial injections in the doses 150 mg and 440 mg. It is intended for intravenous infusion only and not for IV push or bolus.
Exemestane
Description
This page contains brief details about the drug exemestane, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Date of Approval
Exemestane is an anticancer medication that was approved for its medical use on 21st October 1999.
Mechanism of Action of Exemestane
Exemestane is a steroidal agent that belongs to the class of third-generation aromatase inhibitors. The aromatase enzyme is responsible for producing the female sex hormone estrogen. Exemestane irreversibly inactivates the aromatase enzyme, lowers estrogen production, and ultimately slows the development of cancer cells.
Uses of Exemestane
Exemestane Tablet has been developed to treat early and advanced breast cancer in postmenopausal women who have taken Tamoxifen and other treatments before.
Exemestane Dosage available
Exemestane is available as a tablet in a dose of 25mg. Take Exemestane Tablet once a day after food.
Paclitaxel
Description
This page contains brief details about the drug paclitaxel, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Date of Approval
Paclitaxel is a chemotherapeutic anticancer treatment drug which was approved for its medical use on December 1992.
Mechanism of Action of Paclitaxel
Paclitaxel is a chemotherapeutic agent that belongs to the category of medications called microtubule inhibitors. microtubules are structures that aid in the growth and development of cancer cells. Paclitaxel works by inhibiting these structures, ultimately stopping the multiplication of cancer cells. Paclitaxel is prescribed alone and also in combination with other anticancer medications.
Uses of Paclitaxel
Paclitaxel has been developed to treat certain forms of breast cancer, ovarian cancer, non-small cell lung cancer and AIDS-induced Kaposis sarcoma in patients who have not responded well to previous anticancer therapies.
Paclitaxel Dosage available
Paclitaxel is available in the form of injection in the doses 30mg, 100mg, 260mg and 300mg. Your healthcare provider will calculate the ideal dose according to your condition and administer it as an intravenous infusion after dilution.