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Category: Cancer
Gemcitabine
Description
This page contains brief details about the drug gemcitabine, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Date of Approval
The U.S. FDA approved Gemcitabine as a chemotherapeutic anticancer medication to treat bladder, breast, ovarian, pancreatic, and non-small cell lung cancers on 10th January 1995.
Mechanism of Action of Gemcitabine
Gemcitabine is a cytotoxic agent belonging to the category of medications called antimetabolites. It inhibits DNA polymerase enzyme, breaks the DNA strands, interferes with cell signalling and eventually prevents the multiplication of cancer cells. Gemcitabine is prescribed alone and also in combination with other anticancer medications like Cisplatin and Carboplatin.
Uses of Gemcitabine
Gemcitabine has been developed to treat ovarian cancer, breast cancer, non-small cell lung cancer, and pancreatic cancer in patients who have failed to respond to previous therapies.
Gemcitabine Dosage available
Gemcitabine is available for administration as an intravenous infusion that is injected through the veins of patients with ovarian, breast, and non-small cell lung cancer. Your physician will choose the dosage and administration frequency based on your medical condition and type of cancer because it differs for each person.
Ramucirumab
Description
This page contains brief details about the drug ramucirumab, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Date of Approval
Ramucirumab is an anticancer medication containing the active ingredient Ramucirumab. It is a monoclonal antibody drug. Cancer is a condition in which cells multiply uncontrolled and abnormally. This medication treats advanced stomach, colon, rectum, lungs, and liver cancers. It may be given alone or in combination with other anticancer medications to treat various types of cancer. The benefits of Ramucirumab are that it can help to slow down the growth and spread of cancer cells in various types of cancer. Studies have shown that this medication can improve survival rates and increase the time until cancer progresses to the advanced stage.
Ramucirumab was approved by the United States Food and Drug Administration (FDA) in April 2014 for the treatment of advanced gastric or gastroesophageal junction (GEJ) adenocarcinoma, as well as for the treatment of metastatic non-small cell lung cancer (NSCLC) in combination with other anticancer drug.
Mechanism of Action of Ramucirumab
It works by targeting and inhibiting the action of a protein called vascular endothelial growth factor receptor 2 (VEGFR2), which plays a key role in the growth and development of blood vessels that feed tumors. By blocking VEGFR2, ramucirumab helps to prevent the growth and spread of cancer cells.
Uses of Ramucirumab
Ramucirumab is used to treat several types of cancer, including advanced gastric cancer or gastroesophageal junction adenocarcinoma, non-small cell lung cancer, hepatocellular carcinoma, and colorectal cancer.
Ramucirumab Dosage available
A healthcare professional administers Ramucirumab through intravenous injection in a hospital or clinic setting. It is not intended for self-administration. The recommended dosage and frequency depends on the type and stage of the cancer being treated, the individual patient’s medical history, and overall health status. The drug is usually administered with chemotherapy or as a standalone treatment. If you miss a scheduled dose, contact your healthcare provider as soon as possible to discuss the best course of action. Sometimes, your healthcare provider may recommend that you receive the missed dose as soon as possible and then resume the regular dosing schedule. However, this will depend on several factors, such as how long it has been since your last dose, overall health status, and cancer stage. It is important not to double the dose to make up for a missed dose, as this can increase the risk of side effects.
Tamoxifen Citrate
Description
This page contains brief details about the drug tamoxifen citrate, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Date of Approval
Tamoxifen citrate is an anti-estrogen medication developed by the U.S. Food And Drug Administration and initially approved on 29 Oct 1998, for treating breast cancer and infertility.
Mechanism of Action of Tamoxifen Citrate
Tamoxifen citrate Tablet competes with estrogen (sex hormone) for binding to the estrogen receptor, decreases the estrogen receptor-dependent growth in breast tissue, and slows down the growth of cancer cells.
Uses of Tamoxifen Citrate
Tamoxifen citrate helps to treat and prevent breast cancer. It is also used to treat infertility in women caused by a failure to produce and release eggs properly. Cancer is a disorder in which cells multiply in an uncontrolled and abnormal manner.
Tamoxifen Citrate Dosage available
Tamoxifen citrate is a prescription medicine available as a tablet in two doses, Tamoxifen citrate 10mg and 20mg. Do not crush, chew, or open the medicine. Your physician will decide the correct dosage and duration based on age, body weight, and disease condition. Only stop taking the tablet if your doctor advises you to stop.
Filgrastim
Description
This page contains brief details about the drug filgrastim, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Date of Approval
Filgrastim is a granulocyte colony-stimulating factor which was approved for its medical use in 1991 by FDA.
Mechanism of Action of Filgrastim
Filgrastim Injection is a granulocyte colony-stimulating factor that belongs to the group of medications called cytokines. Growth factors are proteins naturally occurring in the body. Filgrastim works by stimulating the bone marrow to produce more white blood cells to fight off infections.
Uses of Filgrastim
Filgrastim decreases the risk of developing febrile neutropenia (occurrence of fever or infection associated with low WBC count) and reduces the duration of neutropenia (low white blood cell count) in people who have non-myeloid cancer and are receiving chemotherapy drugs. It is also used to increase the number of WBC and decrease the length of time of fever in people with acute myeloid leukemia.
It is also used in people undergoing bone marrow transplants and in people with severe chronic neutropenia (low number of neutrophils in the blood). Filgrastim is also used to prepare the blood for leukapheresis (a treatment in which certain blood cells are removed from the blood). It is also indicated to increase the chance of survival in people exposed to harmful amounts of radiation, which can cause severe damage to the bone marrow. Other uses include in patients with advanced HIV infection, which will help to reduce the risk of infections.
Filgrastim Dosage available
Filgrastim is available as a prefilled syringe and solution for injection, intended for subcutaneous or intravenous administration. It is available in a dose 300mcg. The dosing depends on your body weight and severity of illness. your healthcare professional will determine the dose, route of administration, frequency, and duration of treatment based on your disease condition and other factors.
Docetaxel
Description
This page contains brief details about the drug docetaxel, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Date of Approval
Docetaxel is a chemotherapy medication that was approved to be used for its medical use on 19th May 2004.
Mechanism of Action of Docetaxel
Docetaxel works by inhibiting the microtubule structures found in the cells. These microtubules help the cancer cells in proliferating. Hence, inhibition of these structures aids in slowing down the growth of the cancer cells.
Uses of Docetaxel
Docetaxel is indicated for treating different types of cancers, which include the following, non-small cell lung cancer, breast cancer, prostate cancer, stomach cancer and head and neck cancer.
Docetaxel Dosage available
Docetaxel concentrate for solution for infusion (injections) is available in three doses of 20mg, 80mg and 120mg.
Crizotinib
Description
This page contains brief details about the drug crizotinib, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Date of Approval
The U.S. FDA-approved Crizotinib to treat people with ALK-positive NSCLC in the year of 2011.
Mechanism of Action of Crizotinib
Crizotinib Capsule is a biological agent that acts as targeted drug therapy in cancer treatment. It is classified as a tyrosine kinase inhibitor. Anaplastic lymphoma kinase and ROS1 are two prominent genes that result in non-small cell lung cancer by undergoing mutation. Crizotinib acts by inhibiting these genes and stops the growth and development of cancer cells by shrinking them.
Uses of Crizotinib
Crizotinib capsule is indicated to treat the advanced stage of lung cancer as an initial treatment and is also recommended when other anticancer treatments did not work. It is prescribed to treat ALK-positive non-small cell lung cancer (NSCLC)
Crizotinib Dosage available
Crizotinib is available in 200mg and 250mg capsules. The recommended dose is 250mg twice daily, preferably one capsule each in the morning and evening. It is advisable to take this medicine at the same time each day with or without food. Swallow the capsule and do not crush, open, or dissolve them.
Cisplatin
Description
This page contains brief details about the drug cisplatin, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Date of Approval
The U.S. FDA approved Cisplatin as an anticancer medication to treat a certain type of cancer on 19th December 1978.
Mechanism of Action of Cisplatin
Cisplatin belongs to the medication class known as an alkylating agent. It is an anti-cancer medicine that contains the active ingredient Cisplatin. Cisplatin works by stopping the growth and division of cancer cells. It does this by binding to the DNA in the cancer cells and preventing them from replicating.
Uses of Cisplatin
Cisplatin is used to treat testicular tumors, ovarian tumors, bladder tumors, lung cancer, cervical cancer, head and neck epithelial tumors, and. This medicine can prevent the proliferation of cancer cells and prevents cell division which ultimately leads to cell death.
Cisplatin Dosage available Cisplatin injection is administered as an intravenous infusion into the vein. If this injection is recommended for you, it will be given by a healthcare professional. Do not self-administer. Your physician will choose the dosage and administration frequency based on the medical condition because it differs for each person.
Bleomycin
Description
This page contains brief details about the drug bleomycin, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Date of Approval
Bleomycin consists of the active ingredient Bleomycin. It belongs to a group of drugs known as antineoplastic antibiotics. It is commonly used in cancer treatment to slow or stop the growth of cancer cells. It treats lymph node cancers (Hodgkin’s and non-Hodgkin’s lymphoma), head and neck cancer, and cancer in external genitalia. It either be used alone or with radiotherapy and chemotherapy treatment. This injection is also beneficial to prevent and treat the fluid accumulation in the lungs due to cancer.
Bleomycin was first approved by the US Food and Drug Administration (FDA) in 1973 for the treatment of several types of cancer, including Hodgkin’s lymphoma, non-Hodgkin’s lymphoma, squamous cell carcinoma, and testicular cancer. It is also used off-label for treating other types of cancers, such as cervical cancer and melanoma. Bleomycin is a glycopeptide antibiotic that was first isolated from a bacteria named Streptomyces verticillus in 1966.
Mechanism of Action of Bleomycin
Bleomycin is inhibiting cancer cell growth and proliferation. By interfering with DNA replication and transcription, it can slow or stop the growth of cancer cells, leading to their destruction. This effect is particularly important in the treatment of Hodgkin’s lymphoma, non-Hodgkin’s lymphoma, testicular cancer, and some types of lung cancer, where rapid cell growth and division are characteristic features of the disease. Overall, it can help to shrink tumors and improve symptoms in cancer patients.
Uses of Bleomycin
Bleomycin is primarily used to treat several types of cancer, including Hodgkin’s lymphoma, non-Hodgkin’s lymphoma, squamous cell carcinoma, and testicular cancer. It is also used off-label for treating other types of cancers, such as cervical cancer and melanoma. As part of a chemotherapy regimen, it is often used with other drugs to increase its effectiveness. In some cases, it may also be used as a single agent for treating certain cancers. It is particularly effective in the treatment of testicular cancer.
Bleomycin Dosage available
Bleomycin is administered through injection by a healthcare provider in a hospital or clinical setting. The dosage and frequency of administration will vary depending on the type of cancer being treated, the patient’s age and weight, and other factors. It should not be taken orally, as it is not absorbed well through the gastrointestinal tract and may cause serious side effects if ingested.
During treatment, patients should follow their healthcare provider’s instructions closely and attend all scheduled appointments to monitor their condition and response to treatment. If a dose is missed, patients should contact their healthcare provider immediately for instructions on when to take the next dose. It is important not to double the dose to make up for a missed one.
Etoposide
Description
This page contains brief details about the drug etoposide, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Date of Approval
ETOPOSIDEThe U.S. FDA approved Etoposide as an anticancer medication to treat a certain type of cancer on 11th April 1983.
Mechanism of Action of Etoposide
Etoposide works by inhibiting the activity of topoisomerase II (essential for cell replication) and DNA synthesis, which will prevent cancer cells from growing and multiplying, ultimately leading to cell death.
Uses of Etoposide
Etoposide treats testicular, small-cell lung, acute myeloid leukemiaacute myeloid leukemia (blood cancer), Hodgkin’s and non-Hodgkin’s lymphoma, and ovarian cancer. This medicine can prevent the proliferation of cancer cells and prevents cell division which ultimately leads to cell death.
Etoposide Dosage available
It is an intravenous infusion drug that is injected through the veins. Your physician will choose the dosage and administration frequency based on your medical condition because it differs for each person.