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Category: Ovarian Cancer
Epirubicin
Description
This page contains brief details about the drug epirubicin, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Date of Approval
Epirubicin is an antineoplastic drug that belongs to the class anthracyclines. FDA approved epirubicin on November 15, 2006, for the treatment of breast cancer, stomach, and bowel cancer, ovarian cancer, and lung cancer.
Mechanism of Action of Epirubicin
Epirubicin inhibits DNA, RNA, and protein synthesis by exerting cytotoxic activity. It works by slowing or stopping the growth of the cancer cells. This medicine helps to selectively kill the cancer cells rather than the normal, healthy cells.
Uses of Epirubicin
Epirubicin is an intravenously administered drug. This medicine is used as adjuvant therapy in combination with other medications to treat breast cancer in patients who have had surgery to remove the tumor. It is also useful in treating breast, ovaries, stomach, bowel, and lung cancers. In addition, this medicine is also used to treat cancers of the blood-forming tissues, such as malignant lymphomas, leukemias, and multiple myeloma.
Epirubicin Dosage available The drug should be administered only by healthcare professionals experienced with cancer chemotherapy. Your physician will determine the dose and frequency of administration based on the type of cancer and severity of the disease. The medicine will be given as an infusion into a vein. Do not self-administer the injection.
Irinotecan
Description
This page contains brief details about the drug irinotecan, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Date of Approval
Irinotecan is an anti-cancer drug that belongs to the camptothecin analogs. The FDA approved it on August 24, 2004, to treat colon and rectum metastatic carcinoma.
Mechanism of Action of Irinotecan
Irinotecan works by converting its active metabolite with the help of liver enzymes and inhibits the Topoisomerase I enzyme. This causes damage to the DNA synthesis and its replication, thus preventing the cancer cells from growing and spreading.
Uses of Irinotecan
Irinotecan is a topoisomerase enzyme inhibitor used as a first-line therapy in combination with other anti-cancer medications to treat colon and rectum cancers and extensive-stage non-small cell lung cancer. It is also indicated to treat gastric cancers. Irinotecan is currently under investigation to treat ovarian and cervical cancer.
Irinotecan Dosage available
Irinotecan is a prescription drug available as an injection to be administered for over 90 minutes intravenously (into the vein), followed by other chemotherapeutic drugs. The drug will be prescribed and administered by the healthcare professional. It is normally administered no more than once a week, according to the schedule, on which days you receive irinotecan and on which days you dont receive the medication. Your doctor will determine the optimum schedule for you. Antiemetic medications may be given priorly to prevent nausea and vomiting associated with the treatment.
Gemcitabine
Description
This page contains brief details about the drug gemcitabine, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Date of Approval
The U.S. FDA approved Gemcitabine as a chemotherapeutic anticancer medication to treat bladder, breast, ovarian, pancreatic, and non-small cell lung cancers on 10th January 1995.
Mechanism of Action of Gemcitabine
Gemcitabine is a cytotoxic agent belonging to the category of medications called antimetabolites. It inhibits DNA polymerase enzyme, breaks the DNA strands, interferes with cell signalling and eventually prevents the multiplication of cancer cells. Gemcitabine is prescribed alone and also in combination with other anticancer medications like Cisplatin and Carboplatin.
Uses of Gemcitabine
Gemcitabine has been developed to treat ovarian cancer, breast cancer, non-small cell lung cancer, and pancreatic cancer in patients who have failed to respond to previous therapies.
Gemcitabine Dosage available
Gemcitabine is available for administration as an intravenous infusion that is injected through the veins of patients with ovarian, breast, and non-small cell lung cancer. Your physician will choose the dosage and administration frequency based on your medical condition and type of cancer because it differs for each person.
Carboplatin
Description
This page contains brief details about the drug carboplatin, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Date of Approval
The U.S. FDA approved Carboplatin as an anticancer medication to treat certain types of lung and ovarian cancer on 07th April 2003.
Mechanism of Action of Carboplatin
Carboplatin is used alone or with other drugs to treat ovarian cancer. This medication helps in controlling the spread of cancer.
Uses of Carboplatin
Carboplatin acts as an alkylating agent. This medicine inhibits the synthesis of DNA, RNA, and proteins which causes programmed cell death by interrupting DNA replication.
Carboplatin Dosage available
Carboplatin is an intravenous infusion drug that is injected through the veins. Your physician will choose the dosage and administration frequency based on your medical condition because it differs for each person.
Rucaparib
Description
This page contains brief details about the drug rucaparib, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Date of Approval
Rucaparib is an anticancer drug that belongs to the class of medications called PARP (poly ADP-ribose polymerase) inhibitors. FDA approved this medicine on December 19, 2016, to treat certain types of cancers.
Mechanism of Action of Rucaparib
Rucaparib is an inhibitor of poly Adenosine diphosphate-ribose polymerase enzymes, including PARP-1, PARP-2, and PARP-3, which play a role in DNA repair. It blocks an enzyme that repairs damaged DNA in the cancer cells, resulting in their death.
Uses of Rucaparib
Rucaparib is an orally available prescription drug. It is used to help maintain the response to other treatments for certain types of ovarian cancer, fallopian tube (a tube that transports eggs released by the ovaries to the uterus), and primary peritoneal (layer of tissue that lines the abdomen) cancer that has reoccurred in adults who have previously completely responded or partially responded to other chemotherapy treatments.
It is also used to treat certain types of cancer in people with specific gene (BRCA) changes who have received treatment with at least two other chemotherapy treatments. It is also indicated as maintenance therapy immediately after chemotherapy which has caused the tumor to shrink.
Rucaparib Dosage available
It is an orally available antineoplastic drug. The medicine is available as 200mg, 250mg, and 300mg tablets. Your doctor will decide the dose and duration of Rucaparib based on the disease condition and other factors. Always take this medicine as prescribed by your doctor. Take the tablet at the same time, with or without food. Do not break, chew, crush, or break the tablet. Swallow the whole tablet with water.
Paclitaxel
Description
This page contains brief details about the drug paclitaxel, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Date of Approval
Paclitaxel is a chemotherapeutic anticancer treatment drug which was approved for its medical use on December 1992.
Mechanism of Action of Paclitaxel
Paclitaxel is a chemotherapeutic agent that belongs to the category of medications called microtubule inhibitors. microtubules are structures that aid in the growth and development of cancer cells. Paclitaxel works by inhibiting these structures, ultimately stopping the multiplication of cancer cells. Paclitaxel is prescribed alone and also in combination with other anticancer medications.
Uses of Paclitaxel
Paclitaxel has been developed to treat certain forms of breast cancer, ovarian cancer, non-small cell lung cancer and AIDS-induced Kaposis sarcoma in patients who have not responded well to previous anticancer therapies.
Paclitaxel Dosage available
Paclitaxel is available in the form of injection in the doses 30mg, 100mg, 260mg and 300mg. Your healthcare provider will calculate the ideal dose according to your condition and administer it as an intravenous infusion after dilution.