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Emtreo (Treosulfan) Injection
Generic brands for Treosulfan Injection Available in India Brand Name Treoall Generic Name Treosulfan Strength 5mg Manufacturer Hetero Healthcare Ltd
Description
Description
This page contains brief details about the drug treosulfan, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.
Date of Approval
Treosulfan was approved by the FDA for medical use on 04/08/2015 as part of a conditioning treatment for patients undergoing allogeneic hematopoietic stem cell transplantation (allo-HSCT).
Mechanism of Action of Treosulfan
Treosulfan is an alkylating agent. Its mechanism is to cause damage to the DNA structure, leading to inhibition of DNA replication and cancer cell death.
Uses of Treosulfan
Treosulfant is an anti-neoplastic medication belonging to the group called alkylating agents. This medicine is combined with Fludarabine to treat allogeneic hemopoietic stem cell transplant (alloHSCT) in adults with both malignant and non-malignant. In pediatric patients (older than one month), it treats malignant.
Treosulfan Dosage available
Treosulfan injection is administered as an intravenous infusion into the vein. If this injection is recommended for you, it will be given by a healthcare professional. Do not self-administer. Your physician will choose the dosage and administration frequency based on the medical condition because it differs for each person.
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References
- Medexus Inc., [Revised on 25th Jun 2021] [Accessed on 06 May 2023], https://d1io3yog0oux5.cloudfront.net/medexusinc/files/pages/medexusinc/db/795/description/Trecondyv+Product+Monograph.pdf
- Medac, [Accessed on 06 May 2023], https://www.ema.europa.eu/en/documents/product-information/trecondi-epar-product-information_en.pdf
- International Agency for Research on Cancer; Treosulfan; PHARMACEUTICALS; NCBI Bookshelf; [Revised on 2012] [Accessed:06 May 2023]; https://www.ncbi.nlm.nih.gov/books/NBK304322/#_NBK304322_pubdet_
- RA Hilger et al.; Clinical pharmacokinetics of intravenous Treosulfan in patients with advanced solid tumors; [Revised on 1998] [Accessed:06 May 2023] ; https://pubmed.ncbi.nlm.nih.gov/9654108/
- GP Breitbach; Treosulfan in the treatment of advanced ovarian cancer: a randomized co-operative multicentre phase-III study; [Revised on 2002] [Accessed:06 May 2023]; https://pubmed.ncbi.nlm.nih.gov/12530019/