Epitero (Epirubicin) Injection

Generic brands for Epirubicin Injection Available in India Brand Name Epitero Generic Name Epirubicin Strength 10mg, 50mg Manufacturer Hetero Healthcare Ltd

Description

Description

This page contains brief details about the drug epirubicin, it’s indication, dosage & administaration, mechanism of action, related brands with strength, warnings and common side effects.

Date of Approval

Epirubicin is an antineoplastic drug that belongs to the class anthracyclines. FDA approved epirubicin on November 15, 2006, for the treatment of breast cancer, stomach, and bowel cancer, ovarian cancer, and lung cancer.

Mechanism of Action of Epirubicin

Epirubicin inhibits DNA, RNA, and protein synthesis by exerting cytotoxic activity. It works by slowing or stopping the growth of the cancer cells. This medicine helps to selectively kill the cancer cells rather than the normal, healthy cells.

Uses of Epirubicin

Epirubicin is an intravenously administered drug. This medicine is used as adjuvant therapy in combination with other medications to treat breast cancer in patients who have had surgery to remove the tumor. It is also useful in treating breast, ovaries, stomach, bowel, and lung cancers. In addition, this medicine is also used to treat cancers of the blood-forming tissues, such as malignant lymphomas, leukemias, and multiple myeloma.

Epirubicin Dosage available

The drug should be administered only by healthcare professionals experienced with cancer chemotherapy. Your physician will determine the dose and frequency of administration based on the type of cancer and severity of the disease.  The medicine will be given as an infusion into a vein. Do not self-administer the injection.

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References

  1. Epirubicin hydrochloride 2 mg/ml solution for injection – Summary of Product Characteristics (SmPC) – (emc). Medicines.org.uk. [revised on 2016] [cited 2023 Mar 31]. Available from: https://www.medicines.org.uk/emc/product/6361/smpc
  2. HIGHLIGHTS OF PRESCRIBING INFORMATION – Epirubicin. [revised on 2019] [cited 2023 Mar 31]. Available from: https://www.accessdata.fda.gov/drugsatfda_docs/label/2019/050778s024s025lbl.pdf
  3. KD Tripathi, Essentials of Medical Pharmacology, Anticancer drugs, 7th edition, 2013, 867.